The man who had been featured in attention grabbing headlines such as "Du Pont Dominator" and "The Golden Boy of American Cycling," was forced off his bike in excruciating pain in October of 1996. Tests revealed advanced testicular cancer had spread to his lungs and his brain. A press conference on October 9th announced the stunning news to the world. This athletic and vibrant young man would be operated on three times in the ensuing weeks. Chances for his recovery were 50/50 as a frightened, but determined Lance began the most aggressive form of chemotherapy available. It weakened him beyond anything he had experienced, but he had a deep well of reserves and the unconditional support of family and friends. Remarkably, the chemotherapy began to work and Lance allowed his thoughts to return to racing. He began training only five months after his diagnosis, uncertain of his future in the sport, but a profoundly grateful and resolute man.

Cancer left him scarred physically and emotionally, but he now maintains it was an unexpected gift; a viewpoint that is shared by many cancer survivors. Throughout his life threatening ordeal, Lance knew his priorities were changing. His physical well being, something that had never been challenged, was suddenly fragile. He was given the chance to fully appreciate the blessings of good health, a loving family and close friends. Lance described his bout with cancer as "a special wake-up call."